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Research Article

Contribution of Exogenous Genetic Elements to the Group A Streptococcus Metagenome

  • Stephen B. Beres,

    Affiliation: Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America

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  • James M. Musser mail

    To whom correspondence should be addressed. E-mail: jmmusser@tmh.tmc.edu

    Affiliation: Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America

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  • Published: August 29, 2007
  • DOI: 10.1371/journal.pone.0000800
  • Published in PLOS ONE

Reader Comments (4)

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Interaction between small-viral-RNA and streptococcal Metagenome.

Posted by fritze on 06 Oct 2007 at 11:43 GMT

Dear Sir,

the interaction between Picorna (common cold) and Streptococci is well known in praxis.

Until now I understood the viral infection as door-opener of bacterial superinfection.

But could it be possible, that the viral RNA (of Picorna, Influenza or even Hantaa) is incorporated into the Streptococcus Metagenome as a ICE?

1988 and 1996 I observed a resurgence of post-streptococcal-reactive diseases in Göttingen.
Could this be induced by such RNA lateral gene transfer?

Best wishes

Sincerely Yours

Friedrich Flachsbart