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Research Article

Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology

  • Alexander Mellmann equal contributor,

    equal contributor Contributed equally to this work with: Alexander Mellmann, Dag Harmsen, Craig A. Cummings

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Dag Harmsen equal contributor mail,

    equal contributor Contributed equally to this work with: Alexander Mellmann, Dag Harmsen, Craig A. Cummings

    dharmsen@uni-muenster.de

    Affiliation: Department of Periodontology, University Münster, Münster, Germany

    X
  • Craig A. Cummings equal contributor,

    equal contributor Contributed equally to this work with: Alexander Mellmann, Dag Harmsen, Craig A. Cummings

    Affiliation: Life Technologies, Foster City, California, United States of America

    X
  • Emily B. Zentz,

    Affiliation: OpGen, Gaithersburg, Maryland, United States of America

    X
  • Shana R. Leopold,

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Alain Rico,

    Affiliation: Life Technologies, Darmstadt, Germany

    X
  • Karola Prior,

    Affiliation: Department of Periodontology, University Münster, Münster, Germany

    X
  • Rafael Szczepanowski,

    Affiliation: Department of Periodontology, University Münster, Münster, Germany

    X
  • Yongmei Ji,

    Affiliation: Life Technologies, Foster City, California, United States of America

    X
  • Wenlan Zhang,

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Stephen F. McLaughlin,

    Affiliation: Life Technologies, Foster City, California, United States of America

    X
  • John K. Henkhaus,

    Affiliation: OpGen, Gaithersburg, Maryland, United States of America

    X
  • Benjamin Leopold,

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Martina Bielaszewska,

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Rita Prager,

    Affiliation: Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany

    X
  • Pius M. Brzoska,

    Affiliation: Life Technologies, Foster City, California, United States of America

    X
  • Richard L. Moore,

    Affiliation: OpGen, Gaithersburg, Maryland, United States of America

    X
  • Simone Guenther,

    Affiliation: Life Technologies, Darmstadt, Germany

    X
  • Jonathan M. Rothberg,

    Affiliation: Ion Torrent by Life Technologies, Guilford, Connecticut, United States of America

    X
  • Helge Karch

    Affiliation: Institute of Hygiene, University Münster, Münster, Germany

    X
  • Published: July 20, 2011
  • DOI: 10.1371/journal.pone.0022751
  • Published in PLOS ONE

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Media Coverage of This Article

Posted by PLoS_ONE_Group on 29 Jul 2011 at 15:37 GMT

The following articles represent some of the media coverage that has occurred for this paper:

Publication: Science Blogs
Title: “Public Data, Publishing, Priority, and Public Health : Mike the Mad Biologist”
http://scienceblogs.com/m...

Publication: Der Spiegel
Title: “Erbgutanalyse: Forscher entschlüsseln das Ehec-Geheimnis - SPIEGEL ONLINE - Nachrichten - Wissenschaft”
http://www.spiegel.de/wis...

Publication: Zeit Online
Title: “Bakterien-Analyse: Ein ganzes Ehec-Erbgut in 62 Stunden | Wissen | ZEIT ONLINE”
http://www.zeit.de/wissen...

Publication: Nature
Title: “E. coli outbreak strain in genome race : Nature News”
http://www.nature.com/new...

The details below relate to the press release for this paper:

Publication: Press Release
Title: “EHEC 2011 outbreak: Scientists of Münster publish their prospective genomic characterization”
http://www.eurekalert.org...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: Media Coverage of This Article

dharmsen replied to PLoS_ONE_Group on 01 Aug 2011 at 07:08 GMT

Publication: FAZ.net
Title: "Bilanz der Ehec-Krise - Künftig wird man Epidemien anders begegnen"
http://www.faz.net/artike...

Publication: Deutsches Ärzteblatt
Title "EHEC: Aufhebung von Verzehrverboten und Ahnenforschung"
http://www.aerzteblatt.de...

Publication: Hamburger Abendblatt
Title: "EHEC-Erreger ist besonders robust"
http://www.abendblatt.de/...

Publication: BMBF biotechnologie.de
Title: "Erregergenome in Echtzeit: Forscher rekonstruieren Entstehung von EHEC"
http://www.biotechnologie...

Publication: CIDRAP
Title: "Study sheds light on EU outbreak's E coli family tree"
http://www.cidrap.umn.edu...

Publication: Nationale Forschungsplattform für Zoonosen
Title: "EHEC/HUS O104:H4: Ein zoonotischer Erreger verabschiedet sich – aber sein Nachfolger kommt bestimmt"
http://www.zoonosen.net/N...

No competing interests declared.

RE: Media Coverage of This Article

dharmsen replied to PLoS_ONE_Group on 03 Aug 2011 at 07:49 GMT

Publication: In Sequence
Title: "As E. Coli Sequencing Data Accumulates, Teams Disagree on Evolutionary Origins of Outbreak Strain"
http://www.genomeweb.com/...

Publication: The Daily Scan
Title: "Who Are You?"
http://www.genomeweb.com/...

Publication: GenomeWeb Daily News
Title: "Ion Torrent Team Publishes Semiconductor Sequencing Study"
http://www.genomeweb.com/...

Publication: innovations report
Title: "EHEC: Wissenschaftler aus Münster publizieren in PLoS ONE Ergebnisse zur Echtzeit-Genomanalyse"
http://www.innovations-re...

Publication: redOrbit
Title: "EHEC 2011 Outbreak: Scientists Of Münster Publish Their Prospective Genomic Characterization"
http://www.redorbit.com/n...

No competing interests declared.

RE: RE: Media Coverage of This Article

PLoS_ONE_Group replied to dharmsen on 05 Aug 2011 at 15:08 GMT

Further media coverage of this paper can be found below:

Publication: Bacpathgenomics
Title: “E. coli outbreak - PacBio data and PLoS One paper on 2001 O104:H4 strain”
http://bacpathgenomics.wo...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: RE: RE: Media Coverage of This Article

PLoS_ONE_Group replied to PLoS_ONE_Group on 17 May 2013 at 22:20 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: EveryONE PLOS ONE Community Blog
Title: “PLOS ONE Goes to the Mile-High City for ASM 2013 | EveryONE”
http://blogs.plos.org/eve...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff