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Interview

You Say You Want a Revolution: An Interview with Pat Brown

  • Jane Gitschier mail

    jane.gitschier@ucsf.edu

    Affiliation: Departments of Medicine and Pediatrics, Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America

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  • Published: July 17, 2009
  • DOI: 10.1371/journal.pgen.1000560
  • Published in PLOS Genetics

Reader Comments (4)

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Incorrect statement about FISH

Posted by RameshR on 17 Jul 2009 at 17:26 GMT

Gitschier: You obviously aren't color blind. FISH uses just a single fluorescent probe, so why did you feel the need for a two-color, comparative system for the microarrays?
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000560#article1.body1.sec1.p10

Where did you get your information that FISH uses a single fluorescent probe? One of the beauties of FISH is the ability to multiplex probes with different fluorophores, thereby examining multiple loci simultaneously. For an example see http://www.urovysion.com/Results_359.aspx

No competing interests declared.