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Research Article

PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

  • Jaroslav Bendl,

    Affiliations: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic, Department of Information Systems, Faculty of Information Technology, Brno University of Technology, Brno, Czech Republic, Center of Biomolecular and Cellular Engineering, International Centre for Clinical Research, St. Anne's University Hospital Brno, Brno, Czech Republic

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  • Jan Stourac,

    Affiliations: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic, Center of Biomolecular and Cellular Engineering, International Centre for Clinical Research, St. Anne's University Hospital Brno, Brno, Czech Republic

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  • Ondrej Salanda,

    Affiliation: Department of Information Systems, Faculty of Information Technology, Brno University of Technology, Brno, Czech Republic

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  • Antonin Pavelka,

    Affiliation: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic

    Current address: Human-Computer Interaction Laboratory, Department of Computer Graphics and Design, Faculty of Informatics, Masaryk University, Brno, Czech Republic.

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  • Eric D. Wieben,

    Affiliation: Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, New York, United States of America

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  • Jaroslav Zendulka,

    Affiliation: Department of Information Systems, Faculty of Information Technology, Brno University of Technology, Brno, Czech Republic

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  • Jan Brezovsky mail,

    briza@chemi.muni.cz (JB); jiri@chemi.muni.cz (JD)

    Affiliation: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic

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  • Jiri Damborsky mail

    briza@chemi.muni.cz (JB); jiri@chemi.muni.cz (JD)

    Affiliations: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic, Center of Biomolecular and Cellular Engineering, International Centre for Clinical Research, St. Anne's University Hospital Brno, Brno, Czech Republic

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About the Authors

Jaroslav Bendl, Jan Stourac, Antonin Pavelka, Jan Brezovsky, Jiri Damborsky
Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic
Jaroslav Bendl, Ondrej Salanda, Jaroslav Zendulka
Department of Information Systems, Faculty of Information Technology, Brno University of Technology, Brno, Czech Republic
Jaroslav Bendl, Jan Stourac, Jiri Damborsky
Center of Biomolecular and Cellular Engineering, International Centre for Clinical Research, St. Anne's University Hospital Brno, Brno, Czech Republic
Eric D. Wieben
Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JBe JS OS AP EDW JZ JBr JD. Performed the experiments: JBe JS OS. Analyzed the data: JBe JZ JBr JD. Wrote the paper: JBe JBr JD. Contributed the software code: JBe JS. Edited the manuscript: JS OS AP EDW JZ.