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Research Article

SPA: A Probabilistic Algorithm for Spliced Alignment

  • Erik van Nimwegen mail,

    To whom correspondence should be addressed. E-mail: erik.vannimwegen@unibas.ch

    Affiliations: Biozentrum, University of Basel, Basel, Switzerland, Swiss Institute of Bioinformatics, Switzerland

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  • Nicodeme Paul,

    Affiliations: Biozentrum, University of Basel, Basel, Switzerland, Swiss Institute of Bioinformatics, Switzerland

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  • Robert Sheridan,

    Affiliation: The Rockefeller University, New York, New York, United States of America

    ¤ Current address: Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Mihaela Zavolan

    Affiliations: Biozentrum, University of Basel, Basel, Switzerland, Swiss Institute of Bioinformatics, Switzerland

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  • Published: April 28, 2006
  • DOI: 10.1371/journal.pgen.0020024
  • Published in PLOS Genetics

About the Authors

Erik van Nimwegen, Nicodeme Paul, Mihaela Zavolan
Biozentrum, University of Basel, Basel, Switzerland
Erik van Nimwegen, Nicodeme Paul, Mihaela Zavolan
Swiss Institute of Bioinformatics, Switzerland
Robert Sheridan
The Rockefeller University, New York, New York, United States of America

Corresponding Author

Email: erik.vannimwegen@unibas.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

EvN and MZ conceived and designed the experiments. EvN, NP, and MZ performed the experiments. EvN and MZ analyzed the data. NP and RS contributed reagents/materials/analysis tools. EvN and MZ wrote the paper.