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Research Article

Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype

  • Gaelle M. Lefevre,

    Affiliation: Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

    Current address: Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Sanjeevkumar R. Patel,

    Affiliation: Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Doyeob Kim,

    Affiliation: Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

    Current address: CDI Biosciences, Madison, Wisconsin, United States of America

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  • Lino Tessarollo,

    Affiliation: Neural Development Section, National Cancer Institute, Frederick, Maryland, United States of America

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  • Gregory R. Dressler mail

    dressler@umich.edu

    Affiliation: Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Published: October 28, 2010
  • DOI: 10.1371/journal.pgen.1001142
  • Published in PLOS Genetics

About the Authors

Gaelle M. Lefevre, Doyeob Kim, Gregory R. Dressler
Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
Sanjeevkumar R. Patel
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
Lino Tessarollo
Neural Development Section, National Cancer Institute, Frederick, Maryland, United States of America

Corresponding Author

Email: dressler@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GML DK GRD. Performed the experiments: GML SRP DK LT GRD. Analyzed the data: GML SRP GRD. Contributed reagents/materials/analysis tools: LT. Wrote the paper: GRD.