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Research Article

Reconstitution of Mdm2-Dependent Post-Translational Modifications of p53 in Yeast

  • Barbara Di Ventura mail,

    To whom correspondence should be addressed. E-mail: barbara.diventura@bzh.uni-heidelberg.de

    Affiliation: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

    Current address: Biochemistry Center, University of Heidelberg (BZH), Heidelberg, Germany

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  • Charlotta Funaya,

    Affiliation: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

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  • Claude Antony,

    Affiliation: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

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  • Michael Knop,

    Affiliation: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

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  • Luis Serrano

    Affiliation: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

    Current address: Centre de Regulació Genòmica, Barcelona, Spain

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  • Published: January 30, 2008
  • DOI: 10.1371/journal.pone.0001507
  • Published in PLOS ONE

About the Authors

Barbara Di Ventura, Charlotta Funaya, Claude Antony, Michael Knop, Luis Serrano
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

Corresponding Author

Email: barbara.diventura@bzh.uni-heidelberg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BD LS. Performed the experiments: BD. Analyzed the data: BD LS. Contributed reagents/materials/analysis tools: MK CA LS. Wrote the paper: BD. Other: Performed the electron macroscopy experiments: CF.