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Research Article

Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline

  • Thomas Steiner,

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Petra Hess,

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

    Current address: Salutas Pharma GmbH, Barleben, Germany

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  • Jae Hyun Bae,

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

    Current address: Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Birgit Wiltschi,

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Luis Moroder,

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Nediljko Budisa mail

    To whom correspondence should be addressed. E-mail: budisa@biochem.mpg.de

    Affiliation: Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Published: February 27, 2008
  • DOI: 10.1371/journal.pone.0001680
  • Published in PLOS ONE

About the Authors

Thomas Steiner, Petra Hess, Jae Hyun Bae, Birgit Wiltschi, Luis Moroder, Nediljko Budisa
Max Planck Institute of Biochemistry, Martinsried, Germany

Corresponding Author

Email: budisa@biochem.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NB. Performed the experiments: PH JB. Analyzed the data: LM TS BW. Contributed reagents/materials/analysis tools: PH. Wrote the paper: LM BW.