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Research Article

Timing Is Critical for Effective Glucocorticoid Receptor Mediated Repression of the cAMP-Induced CRH Gene

  • Siem van der Laan,

    Affiliation: Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden, The Netherlands

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  • E. Ronald de Kloet,

    Affiliation: Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden, The Netherlands

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  • Onno C. Meijer mail

    o.meijer@lacdr.leidenuniv.nl

    Affiliation: Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden, The Netherlands

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  • Published: January 29, 2009
  • DOI: 10.1371/journal.pone.0004327
  • Published in PLOS ONE

About the Authors

Siem van der Laan, E. Ronald de Kloet, Onno C. Meijer
Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden, The Netherlands

Corresponding Author

Email: o.meijer@lacdr.leidenuniv.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SvdL OCM. Performed the experiments: SvdL. Analyzed the data: SvdL OCM. Wrote the paper: SvdL ERdk OCM.