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Research Article

Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7

  • Tobias Karlberg,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Susanne van den Berg,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Martin Hammarström,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Johanna Sagemark,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Ida Johansson,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Lovisa Holmberg-Schiavone,

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

    Current address: Structural Chemistry Laboratory, AstraZeneca R&D, Mölndal, Sweden

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  • Herwig Schüler mail

    herwig.schuler@ki.se

    Affiliation: Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  • Published: October 20, 2009
  • DOI: 10.1371/journal.pone.0006975
  • Published in PLOS ONE

About the Authors

Tobias Karlberg, Susanne van den Berg, Martin Hammarström, Johanna Sagemark, Ida Johansson, Lovisa Holmberg-Schiavone, Herwig Schüler
Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Corresponding Author

Email: herwig.schuler@ki.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TK LHS HS. Performed the experiments: TK SvdB MH IJ. Analyzed the data: TK HS. Contributed reagents/materials/analysis tools: JS. Wrote the paper: TK HS.