Advertisement
Research Article

A Dynamic Analysis of IRS-PKR Signaling in Liver Cells: A Discrete Modeling Approach

  • Ming Wu equal contributor,

    equal contributor Contributed equally to this work with: Ming Wu, Xuerui Yang

    Affiliation: Department of Computer Science and Engineering, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Xuerui Yang equal contributor,

    equal contributor Contributed equally to this work with: Ming Wu, Xuerui Yang

    Affiliation: Department of Chemical Engineering and Material Science, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Christina Chan mail

    krischan@egr.msu.edu

    Affiliations: Department of Computer Science and Engineering, Michigan State University, East Lansing, Michigan, United States of America, Department of Chemical Engineering and Material Science, Michigan State University, East Lansing, Michigan, United States of America, Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Published: December 01, 2009
  • DOI: 10.1371/journal.pone.0008040
  • Published in PLOS ONE

About the Authors

Ming Wu, Christina Chan
Department of Computer Science and Engineering, Michigan State University, East Lansing, Michigan, United States of America
Xuerui Yang, Christina Chan
Department of Chemical Engineering and Material Science, Michigan State University, East Lansing, Michigan, United States of America
Christina Chan
Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America

Corresponding Author

Email: krischan@egr.msu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MW XY CC. Performed the experiments: MW XY. Analyzed the data: MW XY. Contributed reagents/materials/analysis tools: CC. Wrote the paper: MW XY CC.