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Research Article

Differential DNA Methylation Correlates with Differential Expression of Angiogenic Factors in Human Heart Failure

  • Mehregan Movassagh,

    Affiliation: Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom

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  • Mun-Kit Choy,

    Affiliation: Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom

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  • Martin Goddard,

    Affiliation: Department of Histopathology, Papworth Hospital, Cambridge, United Kingdom

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  • Martin R. Bennett,

    Affiliation: Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom

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  • Thomas A. Down,

    Affiliation: Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

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  • Roger S.-Y. Foo mail

    rsyf2@cam.ac.uk

    Affiliation: Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom

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  • Published: January 13, 2010
  • DOI: 10.1371/journal.pone.0008564
  • Published in PLOS ONE

About the Authors

Mehregan Movassagh, Mun-Kit Choy, Martin R. Bennett, Roger S.-Y. Foo
Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom
Martin Goddard
Department of Histopathology, Papworth Hospital, Cambridge, United Kingdom
Thomas A. Down
Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

Corresponding Author

Email: rsyf2@cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MM MRB RSF. Performed the experiments: MM MkC RSF. Analyzed the data: MM TD. Contributed reagents/materials/analysis tools: MJG. Wrote the paper: RSF.