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Research Article

Structural Biology of Human H3K9 Methyltransferases

  • Hong Wu,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Jinrong Min,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Vladimir V. Lunin,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Tatiana Antoshenko,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Ludmila Dombrovski,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Hong Zeng,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Abdellah Allali-Hassani,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Valérie Campagna-Slater,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Masoud Vedadi,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Cheryl H. Arrowsmith,

    Affiliations: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada, Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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  • Alexander N. Plotnikov mail,

    matthieu.schapira@utoronto.ca (MS); alexander.plotnikov@mssm.edu (ANP)

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

    Current address: Department of Structural and Chemical Biology, Icahn Medical Institute, Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Matthieu Schapira mail

    matthieu.schapira@utoronto.ca (MS); alexander.plotnikov@mssm.edu (ANP)

    Affiliations: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada, Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada

    X
  • Published: January 11, 2010
  • DOI: 10.1371/journal.pone.0008570
  • Published in PLOS ONE

About the Authors

Hong Wu, Jinrong Min, Vladimir V. Lunin, Tatiana Antoshenko, Ludmila Dombrovski, Hong Zeng, Abdellah Allali-Hassani, Valérie Campagna-Slater, Masoud Vedadi, Cheryl H. Arrowsmith, Alexander N. Plotnikov, Matthieu Schapira
Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada
Cheryl H. Arrowsmith
Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Matthieu Schapira
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HW MV AP. Performed the experiments: HW JM VVL TA LD HZ AAH VCS. Analyzed the data: HW CHA AP MS. Wrote the paper: MS.