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Overview

Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

  • Robert J. Prill,

    Affiliation: IBM T. J. Watson Research Center, Yorktown Heights, New York, United States of America

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  • Daniel Marbach,

    Affiliation: Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Julio Saez-Rodriguez,

    Affiliations: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Peter K. Sorger,

    Affiliations: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Leonidas G. Alexopoulos,

    Affiliation: Department of Mechanical Engineering, National Technical University of Athens, Athens, Greece

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  • Xiaowei Xue,

    Affiliation: Genome Institute of Singapore, Singapore, Singapore

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  • Neil D. Clarke,

    Affiliation: Genome Institute of Singapore, Singapore, Singapore

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  • Gregoire Altan-Bonnet,

    Affiliation: Program in Computational Biology and Immunology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Gustavo Stolovitzky mail

    gustavo@us.ibm.com

    Affiliation: IBM T. J. Watson Research Center, Yorktown Heights, New York, United States of America

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  • Published: February 23, 2010
  • DOI: 10.1371/journal.pone.0009202
  • Published in PLOS ONE

About the Authors

Robert J. Prill, Gustavo Stolovitzky
IBM T. J. Watson Research Center, Yorktown Heights, New York, United States of America
Daniel Marbach
Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Julio Saez-Rodriguez, Peter K. Sorger
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
Julio Saez-Rodriguez, Peter K. Sorger
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Leonidas G. Alexopoulos
Department of Mechanical Engineering, National Technical University of Athens, Athens, Greece
Xiaowei Xue, Neil D. Clarke
Genome Institute of Singapore, Singapore, Singapore
Gregoire Altan-Bonnet
Program in Computational Biology and Immunology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Corresponding Author

Email: gustavo@us.ibm.com

Competing Interests

The authors have declared that no competing interests exist.