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Research Article

The Complete Genome Sequence of the Pathogenic Intestinal Spirochete Brachyspira pilosicoli and Comparison with Other Brachyspira Genomes

  • Phatthanaphong Wanchanthuek,

    Affiliations: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia, Faculty of Informatics, Mahasarakham University, Mahasarakham, Thailand

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  • Matthew I. Bellgard,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Tom La,

    Affiliation: Animal Research Institute, School of Veterinary and Biomedical Science, Murdoch University, Perth, Western Australia, Australia

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  • Karon Ryan,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Paula Moolhuijzen,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Brett Chapman,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Michael Black,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • David Schibeci,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Adam Hunter,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Roberto Barrero,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia

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  • Nyree D. Phillips,

    Affiliation: Animal Research Institute, School of Veterinary and Biomedical Science, Murdoch University, Perth, Western Australia, Australia

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  • David J. Hampson mail

    d.hampson@murdoch.edu.au

    Affiliation: Animal Research Institute, School of Veterinary and Biomedical Science, Murdoch University, Perth, Western Australia, Australia

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  • Published: July 06, 2010
  • DOI: 10.1371/journal.pone.0011455
  • Published in PLOS ONE

About the Authors

Phatthanaphong Wanchanthuek, Matthew I. Bellgard, Karon Ryan, Paula Moolhuijzen, Brett Chapman, Michael Black, David Schibeci, Adam Hunter, Roberto Barrero
Centre for Comparative Genomics, Murdoch University, Perth, Western Australia, Australia
Phatthanaphong Wanchanthuek
Faculty of Informatics, Mahasarakham University, Mahasarakham, Thailand
Tom La, Nyree D. Phillips, David J. Hampson
Animal Research Institute, School of Veterinary and Biomedical Science, Murdoch University, Perth, Western Australia, Australia

Corresponding Author

Email: d.hampson@murdoch.edu.au

Competing Interests

This study included identifying bacterial proteins that could be useful for a vaccine. Part of this project was funded by Novartis Animal Vaccines. Several of the proteins that were identified are being patented by Spirogene Pty, a Murdoch University spin-out company. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MIB TL DJH. Performed the experiments: PW TL. Analyzed the data: PW MIB TL KR PMM BC MB DS AH RB NP DJH. Contributed reagents/materials/analysis tools: MIB DS AH. Wrote the paper: PW DJH.