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Research Article

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

  • Hong Wu,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Hong Zeng,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Robert Lam,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Wolfram Tempel,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Maria F. Amaya,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Chao Xu,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Ludmila Dombrovski,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Wei Qiu,

    Affiliation: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada

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  • Yanming Wang,

    Affiliation: Department of Biochemistry and Molecular Biology, Center for Gene Regulation, Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Jinrong Min mail

    jr.min@utoronto.ca

    Affiliations: Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada

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  • Published: June 20, 2011
  • DOI: 10.1371/journal.pone.0018919
  • Published in PLOS ONE

About the Authors

Hong Wu, Hong Zeng, Robert Lam, Wolfram Tempel, Maria F. Amaya, Chao Xu, Ludmila Dombrovski, Wei Qiu, Jinrong Min
Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada
Yanming Wang
Department of Biochemistry and Molecular Biology, Center for Gene Regulation, Pennsylvania State University, University Park, Pennsylvania, United States of America
Jinrong Min
Department of Physiology, University of Toronto, Toronto, Ontario, Canada

Corresponding Author

Email: jr.min@utoronto.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HW JM. Performed the experiments: HW HZ CX RL WT MFA LD WQ. Analyzed the data: HW HZ CX RL WT MFA LD WQ YW JM. Wrote the paper: JM.