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Research Article

Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design

  • Colin A. Smith,

    Affiliations: Graduate Program in Biological and Medical Informatics, University of California San Francisco, San Francisco, California, United States of America, California Institute for Quantitative Biosciences, San Francisco, California, United States of America, Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America

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  • Tanja Kortemme mail

    kortemme@cgl.ucsf.edu

    Affiliations: Graduate Program in Biological and Medical Informatics, University of California San Francisco, San Francisco, California, United States of America, California Institute for Quantitative Biosciences, San Francisco, California, United States of America, Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America

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  • Published: July 18, 2011
  • DOI: 10.1371/journal.pone.0020451
  • Published in PLOS ONE

About the Authors

Colin A. Smith, Tanja Kortemme
Graduate Program in Biological and Medical Informatics, University of California San Francisco, San Francisco, California, United States of America
Colin A. Smith, Tanja Kortemme
California Institute for Quantitative Biosciences, San Francisco, California, United States of America
Colin A. Smith, Tanja Kortemme
Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America

Corresponding Author

Email: kortemme@cgl.ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CAS TK. Performed the experiments: CAS. Analyzed the data: CAS. Contributed reagents/materials/analysis tools: CAS TK. Wrote the paper: CAS TK.