Advertisement
Research Article

Field Performance of a Genetically Engineered Strain of Pink Bollworm

  • Gregory S. Simmons mail,

    gregory.s.simmons@aphis.usda.gov

    Affiliations: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America, Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Moss Landing, California, United States of America

    X
  • Andrew R. McKemey,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Neil I. Morrison,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Sinead O'Connell,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Bruce E. Tabashnik,

    Affiliation: Department of Entomology, University of Arizona, Tucson, Arizona, United States of America

    X
  • John Claus,

    Affiliation: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America

    X
  • Guoliang Fu,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Guolei Tang,

    Affiliation: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America

    X
  • Mickey Sledge,

    Affiliation: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America

    X
  • Adam S. Walker,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Caroline E. Phillips,

    Affiliation: Oxitec Limited, Oxford, United Kingdom

    X
  • Ernie D. Miller,

    Affiliation: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America

    X
  • Robert I. Rose,

    Affiliation: Frederick, Maryland, United States of America

    X
  • Robert T. Staten,

    Affiliation: Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America

    X
  • Christl A. Donnelly,

    Affiliation: Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom

    X
  • Luke Alphey

    Affiliations: Oxitec Limited, Oxford, United Kingdom, Department of Zoology, University of Oxford, Oxford, United Kingdom

    X
  • Published: September 13, 2011
  • DOI: 10.1371/journal.pone.0024110
  • Published in PLOS ONE

About the Authors

Gregory S. Simmons, John Claus, Guolei Tang, Mickey Sledge, Ernie D. Miller, Robert T. Staten
Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Phoenix, Arizona, United States of America
Gregory S. Simmons
Animal Plant Health and Inspection Service, Plant Protection and Quarantine, Centers for Plant Health Science and Technology, United States Department of Agriculture, Moss Landing, California, United States of America
Andrew R. McKemey, Neil I. Morrison, Sinead O'Connell, Guoliang Fu, Adam S. Walker, Caroline E. Phillips, Luke Alphey
Oxitec Limited, Oxford, United Kingdom
Bruce E. Tabashnik
Department of Entomology, University of Arizona, Tucson, Arizona, United States of America
Robert I. Rose
Frederick, Maryland, United States of America
Christl A. Donnelly
Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom
Luke Alphey
Department of Zoology, University of Oxford, Oxford, United Kingdom

Corresponding Author

Email: gregory.s.simmons@aphis.usda.gov

Competing Interests

Those authors affiliated to Oxitec Limited (as noted in the author list) are or were employees of this company, which therefore provided salary and other support for the research program; these authors also have shares or share options in Oxitec Ltd. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GS LA BT RS EM NM AM. Performed the experiments: GS NM SO JC GT MS AW CP. Analyzed the data: CD AM GS. Contributed reagents/materials/analysis tools: EM. Wrote the paper: LA NM GS. Made the DNA constructs: GF. Microinjected DNA to create the engineered pink bollworm line: JC. Generated a homozygous colony of the OX1138B strain: NM SO. Provided regulatory advice: RR.