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Research Article

Postoperative Deterioration in Health Related Quality of Life as Predictor for Survival in Patients with Glioblastoma: A Prospective Study

  • Asgeir S. Jakola mail,

    asgeir.s.jakola@ntnu.no

    Affiliations: Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway, Medical Imaging Lab and Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway

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  • Sasha Gulati,

    Affiliations: Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway, Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway

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  • Clemens Weber,

    Affiliation: Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway

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  • Geirmund Unsgård,

    Affiliations: Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway

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  • Ole Solheim

    Affiliations: Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway, Medical Imaging Lab and Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway

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  • Published: December 09, 2011
  • DOI: 10.1371/journal.pone.0028592
  • Published in PLOS ONE

About the Authors

Asgeir S. Jakola, Sasha Gulati, Clemens Weber, Geirmund Unsgård, Ole Solheim
Department of Neurosurgery, St.Olavs University Hospital, Trondheim, Norway
Asgeir S. Jakola, Ole Solheim
Medical Imaging Lab and Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
Asgeir S. Jakola, Geirmund Unsgård, Ole Solheim
Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
Sasha Gulati
Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway

Corresponding Author

Email: asgeir.s.jakola@ntnu.no

Competing Interests

Prof. Unsgård has approximatly 0.1% of the stocks in SonoWand, the company making the neuronavigation system. All operations were performed under general anesthesia. The SonoWand® neuronavigation system was available if requested by the surgeon and was used in 56 (91.8%) of the operations. There are no patents, products in development, or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: ASJ SG GU OS. Analyzed the data: ASJ SG CW OS. Contributed reagents/materials/analysis tools: ASJ SG CW GU OS. Wrote the paper: ASJ SG CW GU OS.