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Research Article

Cytotoxic T Lymphocyte Trafficking and Survival in an Augmented Fibrin Matrix Carrier

  • Zhaoxia Zou,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Erin Denny,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Christine E. Brown,

    Affiliation: Department of Cancer Immunotherapeutics & Tumor Immunology, City of Hope National Medical Center, Duarte, California, United States of America

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  • Michael C. Jensen,

    Affiliation: Department of Cancer Immunotherapeutics & Tumor Immunology, City of Hope National Medical Center, Duarte, California, United States of America

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  • Gang Li,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Tatsuhiro Fujii,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Josh Neman,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Rahul Jandial,

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Mike Chen mail

    mchen@coh.org

    Affiliation: Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America

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  • Published: April 04, 2012
  • DOI: 10.1371/journal.pone.0034652
  • Published in PLOS ONE

About the Authors

Zhaoxia Zou, Erin Denny, Gang Li, Tatsuhiro Fujii, Josh Neman, Rahul Jandial, Mike Chen
Division of Neurosurgery, City of Hope National Medical Center, Duarte, California, United States of America
Christine E. Brown, Michael C. Jensen
Department of Cancer Immunotherapeutics & Tumor Immunology, City of Hope National Medical Center, Duarte, California, United States of America

Corresponding Author

Email: mchen@coh.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZZ ED MC. Performed the experiments: ZZ ED. Analyzed the data: GL JN RJ. Contributed reagents/materials/analysis tools: CEB MCJ. Wrote the paper: ZZ TF RJ MC.