Advertisement
Research Article

The Impact of Long-Term Exposure to Space Environment on Adult Mammalian Organisms: A Study on Mouse Thyroid and Testis

  • Maria Angela Masini,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Elisabetta Albi,

    Affiliation: Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy

    X
  • Cristina Barmo,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Tommaso Bonfiglio,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Lara Bruni,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Laura Canesi,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Samuela Cataldi,

    Affiliation: Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy

    X
  • Francesco Curcio,

    Affiliation: Department of Clinical and Biological Sciences, University of Udine, Udine, Italy

    X
  • Marta D'Amora,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Ivana Ferri,

    Affiliation: Institute of Pathologic Anatomy and Histology, University of Perugia, Perugia, Italy

    X
  • Katsumasa Goto,

    Affiliation: School of Health Sciences, Toyohashi SOZO University, Aichi, Japan

    X
  • Fuminori Kawano,

    Affiliation: Graduate School of Medicine, Osaka University, Osaka, Japan

    X
  • Remo Lazzarini,

    Affiliation: Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy

    X
  • Elisabetta Loreti,

    Affiliation: Institute of Pathologic Anatomy and Histology, University of Perugia, Perugia, Italy

    X
  • Naoya Nakai,

    Affiliation: Graduate School of Medicine, Osaka University, Osaka, Japan

    X
  • Takashi Ohira,

    Affiliation: Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

    X
  • Yoshinobu Ohira,

    Affiliations: Graduate School of Medicine, Osaka University, Osaka, Japan, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

    X
  • Silvio Palmero,

    Affiliation: DIBIO, University of Genoa, Genova, Italy

    X
  • Paola Prato,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Franco Ricci,

    Affiliation: ENEA-C.R. Casaccia, Roma, Italy

    X
  • Linda Scarabelli,

    Affiliation: DIPTERIS, University of Genoa, Genova, Italy

    X
  • Tsubasa Shibaguchi,

    Affiliation: Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

    X
  • Renza Spelat,

    Affiliation: Department of Clinical and Biological Sciences, University of Udine, Udine, Italy

    X
  • Felice Strollo,

    Affiliation: INRCA-IRCCS, Roma, Italy

    X
  • Francesco Saverio Ambesi-Impiombato mail

    ambesi@uniud.it

    Affiliation: Department of Clinical and Biological Sciences, University of Udine, Udine, Italy

    X
  • Published: April 25, 2012
  • DOI: 10.1371/journal.pone.0035418
  • Published in PLOS ONE

About the Authors

Maria Angela Masini, Cristina Barmo, Tommaso Bonfiglio, Lara Bruni, Laura Canesi, Marta D'Amora, Paola Prato, Linda Scarabelli
DIPTERIS, University of Genoa, Genova, Italy
Elisabetta Albi, Samuela Cataldi, Remo Lazzarini
Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Francesco Curcio, Renza Spelat, Francesco Saverio Ambesi-Impiombato
Department of Clinical and Biological Sciences, University of Udine, Udine, Italy
Ivana Ferri, Elisabetta Loreti
Institute of Pathologic Anatomy and Histology, University of Perugia, Perugia, Italy
Katsumasa Goto
School of Health Sciences, Toyohashi SOZO University, Aichi, Japan
Fuminori Kawano, Naoya Nakai, Yoshinobu Ohira
Graduate School of Medicine, Osaka University, Osaka, Japan
Takashi Ohira, Yoshinobu Ohira, Tsubasa Shibaguchi
Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
Silvio Palmero
DIBIO, University of Genoa, Genova, Italy
Franco Ricci
ENEA-C.R. Casaccia, Roma, Italy
Felice Strollo
INRCA-IRCCS, Roma, Italy

Corresponding Author

Email: ambesi@uniud.it

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MAM EA YO FSAI. Performed the experiments: MAM EA CB TB LB LC SC FC MDA IF KG FK RL EL NN TO YO SP PP FR LS TS RS FS FSAI. Analyzed the data: MAM EA CB TB LB LC SC FC MDA IF KG FK RL EL NN TO YO SP PP FR LS TS RS FS FSAI. Contributed reagents/materials/analysis tools: MAM EA CB TB LB LC SC FC MDA IF KG FK RL EL NN TO YO SP PP FR LS TS RS FS FSAI. Wrote the paper: MAM EA YO FSAI.