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Research Article

Epigenetic Analysis of KSHV Latent and Lytic Genomes

  • Zsolt Toth,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Dennis T. Maglinte,

    Affiliation: USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Sun Hwa Lee,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Hye-Ra Lee,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Lai-Yee Wong,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Kevin F. Brulois,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Stacy Lee,

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Jonathan D. Buckley,

    Affiliations: USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Peter W. Laird,

    Affiliation: USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Victor E. Marquez,

    Affiliation: Laboratory of Medicinal Chemistry, Center for Cancer Research, NCI-Frederick, Frederick, Maryland, United States of America

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  • Jae U. Jung mail

    jaeujung@usc.edu

    Affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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  • Published: July 22, 2010
  • DOI: 10.1371/journal.ppat.1001013
  • Published in PLOS Pathogens

About the Authors

Zsolt Toth, Sun Hwa Lee, Hye-Ra Lee, Lai-Yee Wong, Kevin F. Brulois, Stacy Lee, Jae U. Jung
Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
Dennis T. Maglinte, Jonathan D. Buckley, Peter W. Laird
USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
Jonathan D. Buckley
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
Victor E. Marquez
Laboratory of Medicinal Chemistry, Center for Cancer Research, NCI-Frederick, Frederick, Maryland, United States of America

Corresponding Author

Email: jaeujung@usc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZT JUJ. Performed the experiments: ZT. Analyzed the data: ZT DTM. Contributed reagents/materials/analysis tools: ZT DTM SHL HRL LYW KFB JDB PWL VEM. Wrote the paper: ZT SL JUJ.