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Research Article

Transcriptome Analysis of Aedes aegypti Transgenic Mosquitoes with Altered Immunity

  • Zhen Zou equal contributor,

    equal contributor Contributed equally to this work with: Zhen Zou, Jayme Souza-Neto

    Affiliation: Department of Entomology and the Institute for Integrative Genome Biology, University of California, Riverside, California, United States of America

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  • Jayme Souza-Neto equal contributor,

    equal contributor Contributed equally to this work with: Zhen Zou, Jayme Souza-Neto

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

    Current address: Center for Technological Development in Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

    X
  • Zhiyong Xi,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

    Current address: Department of Entomology, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Vladimir Kokoza,

    Affiliation: Department of Entomology and the Institute for Integrative Genome Biology, University of California, Riverside, California, United States of America

    X
  • Sang Woon Shin,

    Affiliation: Department of Entomology and the Institute for Integrative Genome Biology, University of California, Riverside, California, United States of America

    X
  • George Dimopoulos mail,

    gdimopou@jhsph.edu (GD); alexander.raikhel@ucr.edu (AR)

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

    X
  • Alexander Raikhel mail

    gdimopou@jhsph.edu (GD); alexander.raikhel@ucr.edu (AR)

    Affiliation: Department of Entomology and the Institute for Integrative Genome Biology, University of California, Riverside, California, United States of America

    X
  • Published: November 17, 2011
  • DOI: 10.1371/journal.ppat.1002394
  • Published in PLOS Pathogens

About the Authors

Zhen Zou, Vladimir Kokoza, Sang Woon Shin, Alexander Raikhel
Department of Entomology and the Institute for Integrative Genome Biology, University of California, Riverside, California, United States of America
Jayme Souza-Neto, Zhiyong Xi, George Dimopoulos
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AR GD. Performed the experiments: ZZ JSN ZX VK SWS. Analyzed the data: ZZ JSN ZX GD AR. Contributed reagents/materials/analysis tools: ZZ JSN ZX VK GD. Wrote the paper: ZZ JSN GD AR.