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Table of Contents: World Health Report 2012: No Health Without Research

COVER

Image Credit: Permission kindly granted by WHO for use of their logo; image compilation by PLOS.
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In January 2011 the PLOS Medicine editors announced a collaboration with the World Health Organization (WHO) on the theme of research for better health. Submissions were invited to the WHO/PLOS collection “No Health Without Research”, which was intended to culminate in 2012 to coincide with the release of the 2012 World Health Report by WHO, which would also address the same topic.

The collection's theme is oriented around the fact that decisions on healthcare are still made without a solid grounding in research evidence, and an impetus is required for this state of affairs to change. The collection focuses on eight specific areas, discussed in the editorial announcing the Call for Papers, within the theme of 'No Health Without Research'. Articles below include examples previously published in PLOS journals in these specific areas of interest, along with articles submitted in response to the Call for Papers and subsequently published in PLOS journals, and evaluated by a joint PLOS Medicine/WHO panel as being appropriate to the original collection theme. WHO panellists were Robert F. Terry and Tikki Pang.

A closing editorial summarises the history of the collection and how this relates to the next World Health Report. The Call for Papers is now closed.

Editorials

WHO/PLoS Collection “No Health Without Research”: A Call for Papers

Tikki Pang, Robert F. Terry , The PLoS Medicine Editors

The PLoS Medicine Debate

Are Patents Impeding Medical Care and Innovation?

E. Richard Gold, Warren Kaplan, James Orbinski, Sarah Harland-Logan, Sevil N-Marandi

Viewpoints

Clinical Research in Resource-Limited Settings: Enhancing Research Capacity and Working Together to Make Trials Less Complicated

Trudie A. Lang, Nicholas J. White, Tran Tinh Hien, Jeremy J. Farrar, Nicholas P. J. Day, Raymond Fitzpatrick, Brian J. Angus, Emmanuelle Denis, Laura Merson, Phaik Yeong Cheah, Roma Chilengi, Robert Kimutai, Kevin Marsh

Essays

Health in Action

AIDS Vaccine for Asia Network (AVAN): Expanding the Regional Role in Developing HIV Vaccines

Stephen J. Kent, David A. Cooper, Mean Chhi Vun, Yiming Shao, Linqi Zhang, Nirmal Ganguly, Budiman Bela, Hiko Tamashiro, Rossana Ditangco, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Nguyen Van Kinh, Alan Bernstein, Saladin Osmanov , for the AIDS Vaccine for Asia Network investigators and supporters

A Field Training Guide for Human Subjects Research Ethics

Maria W. Merritt, Alain B. Labrique, Joanne Katz, Mahbubur Rashid, Keith P. West Jr., Joan Pettit

Developing ANDI: A Novel Approach to Health Product R&D in Africa

Solomon Nwaka, Tshinko B. Ilunga, Jorge Santos Da Silva, Emiliano Rial Verde, Doan Hackley, Raymond De Vré, Tom Mboya-Okeyo, Robert G. Ridley

Laboratory Capacity Building in Asia for Infectious Disease Research: Experiences from the South East Asia Infectious Disease Clinical Research Network (SEAICRN)

Heiman F. L. Wertheim, Pilaipan Puthavathana, Ngoc My Nghiem, H. Rogier van Doorn, Trung Vu Nguyen, Hung Viet Pham, Decy Subekti, Syahrial Harun, Suhud Malik, Janet Robinson, Motiur Rahman, Walter Taylor, Niklas Lindegardh, Steve Wignall, Jeremy J. Farrar, Menno D. de Jong

Strengthening the Informed Consent Process in International Health Research through Community Engagement: The KEMRI-Wellcome Trust Research Programme Experience

Mwanamvua Boga, Alun Davies, Dorcas Kamuya, Samson M. Kinyanjui, Ester Kivaya, Francis Kombe, Trudie Lang, Vicki Marsh, Bibi Mbete, Albert Mlamba, Sassy Molyneux, Stephen Mulupi, Salim Mwalukore

Policy Platform

Research and Capacity Building for Control of Neglected Tropical Diseases: The Need for a Different Approach

Thomas Kariuki, Richard Phillips, Sammy Njenga, Ole F. Olesen, Paul R. Klatser, Riccardo Porro, Sarah Lock, Maria Hermínia Cabral, Martina Gliber, Detlef Hanne

Policy Forums

Registering New Drugs for Low-Income Countries: The African Challenge

Mary Moran, Nathalie Strub-Wourgaft, Javier Guzman, Pascale Boulet, Lindsey Wu, Bernard Pecoul

Defining Research to Improve Health Systems

Jan H. F. Remme, Taghreed Adam, Francisco Becerra-Posada, Catherine D'Arcangues, Michael Devlin, Charles Gardner, Abdul Ghaffar, Joachim Hombach, Jane F. K. Kengeya, Anthony Mbewu, Michael T. Mbizvo, Zafar Mirza, Tikki Pang, Robert G. Ridley, Fabio Zicker, Robert F. Terry

The Global Health System: Lessons for a Stronger Institutional Framework

Suerie Moon, Nicole A. Szlezák, Catherine M. Michaud, Dean T. Jamison, Gerald T. Keusch, William C. Clark, Barry R. Bloom

The Global Health System: Linking Knowledge with Action—Learning from Malaria

Gerald T. Keusch, Wen L. Kilama, Suerie Moon, Nicole A. Szlezák, Catherine M. Michaud

Assessing and Strengthening African Universities' Capacity for Doctoral Programmes

Imelda Bates, Richard Phillips, Ruby Martin-Peprah, Gibson Kibiki, Oumar Gaye, Kamija Phiri, Harry Tagbor, Sue Purnell

Building the Field of Health Policy and Systems Research: An Agenda for Action

Sara Bennett, Irene Akua Agyepong, Kabir Sheikh, Kara Hanson, Freddie Ssengooba, Lucy Gilson

Building the Field of Health Policy and Systems Research: Social Science Matters

Lucy Gilson, Kara Hanson, Kabir Sheikh, Irene Akua Agyepong, Freddie Ssengooba, Sara Bennett

Building the Field of Health Policy and Systems Research: Framing the Questions

Kabir Sheikh, Lucy Gilson, Irene Akua Agyepong, Kara Hanson, Freddie Ssengooba, Sara Bennett

Priorities for Research on Equity and Health: Towards an Equity-Focused Health Research Agenda

Piroska Östlin, Ted Schrecker, Ritu Sadana, Josiane Bonnefoy, Lucy Gilson, Clyde Hertzman, Michael P. Kelly, Tord Kjellstrom, Ronald Labonté, Olle Lundberg, Carles Muntaner, Jennie Popay, Gita Sen, Ziba Vaghri

What Research Is Needed to Stop TB? Introducing the TB Research Movement

Christian Lienhardt, Marcos Espinal, Madhukar Pai, Dermot Maher, Mario C. Raviglione

Responsible Governance for Mental Health Research in Low Resource Countries

M. Taghi Yasamy, Pallab K. Maulik, Mark Tomlinson, Crick Lund, Mark Van Ommeren, Shekhar Saxena

Guidance for Evidence-Informed Policies about Health Systems: Rationale for and Challenges of Guidance Development

Xavier Bosch-Capblanch, John N. Lavis, Simon Lewin, Rifat Atun, John-Arne Røttingen, Daniel Dröschel, Lise Beck, Edgardo Abalos, Fadi El-Jardali, Lucy Gilson, Sandy Oliver, Kaspar Wyss, Peter Tugwell, Regina Kulier, Tikki Pang, Andy Haines

Guidelines and Guidance

Setting Research Priorities to Reduce Almost One Million Deaths from Birth Asphyxia by 2015

Joy E. Lawn, Rajiv Bahl, Staffan Bergstrom, Zulfiqar A. Bhutta, Gary L. Darmstadt, Matthew Ellis, Mike English, Jennifer J. Kurinczuk, Anne C. C. Lee, Mario Merialdi, Mohamed Mohamed, David Osrin, Robert Pattinson, Vinod Paul, Siddarth Ramji, Ola D. Saugstad, Lyn Sibley, Nalini Singhal, Steven N. Wall, Dave Woods, John Wyatt, Kit Yee Chan, Igor Rudan

Setting Implementation Research Priorities to Reduce Preterm Births and Stillbirths at the Community Level

Asha George, Mark Young, Abhay Bang, Kit Yee Chan, Igor Rudan, Cesar G. Victora, Mickey Chopra, Craig Rubens , and the GAPPS expert group on community based strategies and constraints

Research Priorities for Mental Health and Psychosocial Support in Humanitarian Settings

Wietse A. Tol, Vikram Patel, Mark Tomlinson, Florence Baingana, Ananda Galappatti, Catherine Panter-Brick, Derrick Silove, Egbert Sondorp, Michael Wessells, Mark van Ommeren

Setting Research Priorities to Reduce Global Mortality from Childhood Pneumonia by 2015

Igor Rudan, Shams El Arifeen, Zulfiqar A. Bhutta, Robert E. Black, Abdullah Brooks, Kit Yee Chan, Mickey Chopra, Trevor Duke, David Marsh, Antonio Pio, Eric A.F. Simoes, Giorgio Tamburlini, Evropi Theodoratou, Martin W. Weber, Cynthia G. Whitney, Harry Campbell, Shamim A. Qazi , and the WHO/CHNRI Expert Group on Childhood Pneumonia

Symposium

Franchising Rabies Vaccine Delivery: The Case of Indian Immunologicals

Hassan Masum, Hima Batavia, Natasha Bhogal, Kim Le, Peter A. Singer

Reviews

A Research Agenda to Underpin Malaria Eradication

Pedro L. Alonso, Graham Brown, Myriam Arevalo-Herrera, Fred Binka, Chetan Chitnis, Frank Collins, Ogobara K. Doumbo, Brian Greenwood, B. Fenton Hall, Myron M. Levine, Kamini Mendis, Robert D. Newman, Christopher V. Plowe, Mario Henry Rodríguez, Robert Sinden, Laurence Slutsker, Marcel Tanner

The NIH-NIAID Filariasis Research Reagent Resource Center

Michelle L. Michalski, Kathryn G. Griffiths, Steven A. Williams, Ray M. Kaplan, Andrew R. Moorhead

Voluntary Medical Male Circumcision: Translating Research into the Rapid Expansion of Services in Kenya, 2008–2011

Zebedee Mwandi, Anne Murphy, Jason Reed, Kipruto Chesang, Emmanuel Njeuhmeli, Kawango Agot, Emma Llewellyn, Charles Kirui, Kennedy Serrem, Isaac Abuya, Mores Loolpapit, Regina Mbayaki, Ndungu Kiriro, Peter Cherutich, Nicholas Muraguri, John Motoku, Jack Kioko, Nancy Knight, Naomi Bock

Research Articles

Reduction of Severe Acute Maternal Morbidity and Maternal Mortality in Thyolo District, Malawi: The Impact of Obstetric Audit

Thomas van den Akker, Jair van Rhenen, Beatrice Mwagomba, Kinke Lommerse, Steady Vinkhumbo, Jos van Roosmalen

NIH Disease Funding Levels and Burden of Disease

Leslie A. Gillum, Christopher Gouveia, E. Ray Dorsey, Mark Pletcher, Colin D. Mathers, Charles E. McCulloch, S. Claiborne Johnston

Strategies for Increasing Recruitment to Randomised Controlled Trials: Systematic Review

Patrina H. Y. Caldwell, Sana Hamilton, Alvin Tan, Jonathan C. Craig

Development of and Access to Products for Neglected Diseases

Joshua Cohen, Maria Staroselsky Dibner, Andrew Wilson

Research Ethics Training in Peru: A Case Study

A. Roxana Lescano, David L. Blazes, Silvia M. Montano, Zoe Moran, Cesar Naquira, Edwin Ramirez, Reidar Lie, Gregory J. Martin, Andres G. Lescano, Joseph R. Zunt

Lessons from History for Designing and Validating Epidemiological Surveillance in Uncounted Populations

Peter Byass, Osman Sankoh, Stephen M. Tollman, Ulf Högberg, Stig Wall

The Use of Research Evidence in Public Health Decision Making Processes: Systematic Review

Lois Orton, Ffion Lloyd-Williams, David Taylor-Robinson, Martin O'Flaherty, Simon Capewell

Repeated Assessments of Informed Consent Comprehension among HIV-Infected Participants of a Three-Year Clinical Trial in Botswana

Lelia H. Chaisson, Nancy E. Kass, Bafanana Chengeta, Unami Mathebula, Taraz Samandari

Impact of Health Research Capacity Strengthening in Low- and Middle-Income Countries: The Case of WHO/TDR Programmes

Happiness Minja, Christian Nsanzabana, Christine Maure, Axel Hoffmann, Susan Rumisha, Olumide Ogundahunsi, Fabio Zicker, Marcel Tanner, Pascal Launois

Trends in Health Policy and Systems Research over the Past Decade: Still Too Little Capacity in Low-Income Countries

Taghreed Adam, Saad Ahmad, Maryam Bigdeli, Abdul Ghaffar, John-Arne Røttingen

Access to Scientific Publications: The Scientist's Perspective

Yegor Voronin, Askar Myrzahmetov, Alan Bernstein

A Collaboratively-Derived Science-Policy Research Agenda

William J. Sutherland, Laura Bellingan, Jim R. Bellingham, Jason J. Blackstock, Robert M. Bloomfield, Michael Bravo, Victoria M. Cadman, David D. Cleevely, Andy Clements, Anthony S. Cohen, David R. Cope, Arthur A. Daemmrich, Cristina Devecchi, Laura Diaz Anadon, Simon Denegri, Robert Doubleday, Nicholas R. Dusic, Robert J. Evans, Wai Y. Feng, H. Charles J. Godfray, Paul Harris, Sue E. Hartley, Alison J. Hester, John Holmes, Alan Hughes, Mike Hulme, Colin Irwin, Richard C. Jennings, Gary S. Kass, Peter Littlejohns, Theresa M. Marteau, Glenn McKee, Erik P. Millstone, William J. Nuttall, Susan Owens, Miles M. Parker, Sarah Pearson, Judith Petts, Richard Ploszek, Andrew S. Pullin, Graeme Reid, Keith S. Richards, John G. Robinson, Louise Shaxson, Leonor Sierra, Beck G. Smith, David J. Spiegelhalter, Jack Stilgoe, Andy Stirling, Christopher P. Tyler, David E. Winickoff, Ron L. Zimmern

Identifying Trustworthy Experts: How Do Policymakers Find and Assess Public Health Researchers Worth Consulting or Collaborating With?

Abby S. Haynes, Gemma E. Derrick, Sally Redman, Wayne D. Hall, James A. Gillespie, Simon Chapman, Heidi Sturk