Advertisement

Table of Contents: PLoS Neglected Tropical Diseases: A Research Agenda for the Control and Elimination of Human Helminthiases

COVER

Image Credit: Montage created by Pat Margis, Public Library of Science. Original images by (clockwise from top left) Centers for Disease Control, Centers for Disease Control, Dr. Banchob Sripa (Khon Kaen University, Thailand), Dr. Héctor H. García (Universidad Peruana Cayetano Heredia, Lima, Peru), WHO/TDR/OCP, Dr. Mark L. Eberhard (CDC/CGH/DPDM, Atlanta, USA)
Issue Image

More than half of the world's population is at risk of helminthiases, and hundreds of millions of people are currently infected with one or more helminth species. Consequences of chronic infection include suffering, stigmatization, subtle and gross morbidity, and premature death. These infections are associated with low work productivity, poor cognitive performance, and slow socioeconomic development, thereby contributing to accentuate poverty and inequality. In the April 2012 issue of PLoS Neglected Tropical Diseases, the Disease Reference Group on Helminth Infections (DRG4) put forward a series of eight reviews that, taken together, outline a compelling research and development (R&D) agenda for the control and elimination of helminth diseases of humans. Emphasis is placed on six major helminth diseases: soil-transmitted helminthiasis; schistosomiasis; lymphatic filariasis; onchocerciasis; food-borne trematodiasis; and cysticercosis/taeniasis. Additionally, an Editorial from Jürg Utzinger provides an overview to all eight reviews and emphasizes the importance of continued research on these six diseases, which together have an enormous global health impact.

DRG4 is part of an independent “think tank” of international experts, established and funded by the Special Programme for Research and Training in Tropical Diseases (TDR), to identify key research priorities through the review of research evidence and input from stakeholder consultations. For more information on the TDR Think Tank and the resulting reports, please visit: http://www.who.int/tdr/stewardship/research-think-tank/en/.

Editorial

Reviews

A Research Agenda for Helminth Diseases of Humans: Towards Control and Elimination

Boakye A. Boatin, María-Gloria Basáñez, Roger K. Prichard, Kwablah Awadzi, Rashida M. Barakat, Héctor H. García, Andrea Gazzinelli, Warwick N. Grant, James S. McCarthy, Eliézer K. N'Goran, Mike Y. Osei-Atweneboana, Banchob Sripa, Guo-Jing Yang, Sara Lustigman

A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases

Sara Lustigman, Roger K. Prichard, Andrea Gazzinelli, Warwick N. Grant, Boakye A. Boatin, James S. McCarthy, María-Gloria Basáñez

A Research Agenda for Helminth Diseases of Humans: Intervention for Control and Elimination

Roger K. Prichard, María-Gloria Basáñez, Boakye A. Boatin, James S. McCarthy, Héctor H. García, Guo-Jing Yang, Banchob Sripa, Sara Lustigman

A Research Agenda for Helminth Diseases of Humans: Diagnostics for Control and Elimination Programmes

James S. McCarthy, Sara Lustigman, Guo-Jing Yang, Rashida M. Barakat, Héctor H. García, Banchob Sripa, Arve Lee Willingham, Roger K. Prichard, María-Gloria Basáñez

A Research Agenda for Helminth Diseases of Humans: Social Ecology, Environmental Determinants, and Health Systems

Andrea Gazzinelli, Rodrigo Correa-Oliveira, Guo-Jing Yang, Boakye A. Boatin, Helmut Kloos

A Research Agenda for Helminth Diseases of Humans: Modelling for Control and Elimination

María-Gloria Basáñez, James S. McCarthy, Michael D. French, Guo-Jing Yang, Martin Walker, Manoj Gambhir, Roger K. Prichard, Thomas S. Churcher

A Research Agenda for Helminth Diseases of Humans: Basic Research and Enabling Technologies to Support Control and Elimination of Helminthiases

Sara Lustigman, Peter Geldhof, Warwick N. Grant, Mike Y. Osei-Atweneboana, Banchob Sripa, María-Gloria Basáñez

A Research Agenda for Helminth Diseases of Humans: Health Research and Capacity Building in Disease-Endemic Countries for Helminthiases Control

Mike Y. Osei-Atweneboana, Sara Lustigman, Roger K. Prichard, Boakye A. Boatin, María-Gloria Basáñez