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Genomics of Emerging Infectious Disease

This collection of essays, perspectives, and reviews from six PLoS Journals provides insights into how genomics can revolutionize our understanding of emerging infectious disease.

Collection Editor: Jonathan A. Eisen, PhD, is a Professor at the University of California, Davis, in Davis, California. His laboratory is in the UC Davis Genome Center, and he holds appointments in the Section of Evolution and Ecology and the Department of Medical Microbiology and Immunology.

Staff Editor: Catriona J. MacCallum; Developmental Editor: Carol Featherstone, PhD (Freelance Science Editor and Writer); Copy Editor: Maggie Brown.

Downloads: Audio interview (22 minutes; 10 MB MP3) with Jonathan Eisen, Siv Andersson, and Raj Gupta, led by Kirsten Sanford; Complete collection (6.7 MB PDF).

Produced with support from Google.org. The PLoS Journal editors have sole responsibility for the content of this collection.

Image Credit: Illustration by Pat Margis (PLoS) of a double helix with superimposed images from articles in this collection. Top: a human helminth (Strongyloides stercoralis) from Brindley et al., PLoS Negl Trop Dis 3(10) e538. Center: a schematic representation of an influenza A virion from McHardy et al., PLoS Pathog 5(10) e1000566. Bottom: the bacterium Helicobacter pylori from Dorer et al., PLoS Pathog 5(10) e1000544.

 
 

Editorial Top

Genomics of Emerging Infectious Disease: A PLoS Collection

Jonathan A. Eisen, Catriona J. MacCallum

PLoS Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pbio.1000224
 

Essay Top

Molecular Genomic Approaches to Infectious Diseases in Resource-Limited Settings

Josefina Coloma, Eva Harris

PLoS Medicine:
Published 26 Oct 2009 | info:doi/10.1371/journal.pmed.1000142
 

Perspectives Top

Can an Infectious Disease Genomics Project Predict and Prevent the Next Pandemic?

Rajesh Gupta, Mark H. Michalski, Frank R. Rijsberman

PLoS Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pbio.1000219

The Role of Genomics in the Identification, Prediction, and Prevention of Biological Threats

W. Florian Fricke, David A. Rasko, Jacques Ravel

PLoS Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pbio.1000217

Discovering the Phylodynamics of RNA Viruses

Edward C. Holmes, Bryan T. Grenfell

PLoS Computational Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pcbi.1000505

Computational Resources in Infectious Disease: Limitations and Challenges

Eva C. Berglund, Björn Nystedt, Siv G. E. Andersson

PLoS Computational Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pcbi.1000481

The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

Wesley C. Van Voorhis, Wim G. J. Hol, Peter J. Myler, Lance J. Stewart

PLoS Computational Biology:
Published 26 Oct 2009 | info:doi/10.1371/journal.pcbi.1000530
 

Reviews Top

The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases

Kate L. Seib, Gordon Dougan, Rino Rappuoli

PLoS Genetics:
Published 26 Oct 2009 | info:doi/10.1371/journal.pgen.1000612

Toward the Use of Genomics to Study Microevolutionary Change in Bacteria

Daniel Falush

PLoS Genetics:
Published 26 Oct 2009 | info:doi/10.1371/journal.pgen.1000627

The Application of Genomics to Emerging Zoonotic Viral Diseases

Bart L. Haagmans, Arno C. Andeweg, Albert D. M. E. Osterhaus

PLoS Pathogens:
Published 26 Oct 2009 | info:doi/10.1371/journal.ppat.1000557

The Role of Genomics in Tracking the Evolution of Influenza A Virus

Alice Carolyn McHardy, Ben Adams

PLoS Pathogens:
Published 26 Oct 2009 | info:doi/10.1371/journal.ppat.1000566

The Past and Future of Tuberculosis Research

Iñaki Comas, Sebastien Gagneux

PLoS Pathogens:
Published 26 Oct 2009 | info:doi/10.1371/journal.ppat.1000600

Helicobacter pylori's Unconventional Role in Health and Disease

Marion S. Dorer, Sarah Talarico, Nina R. Salama

PLoS Pathogens:
Published 26 Oct 2009 | info:doi/10.1371/journal.ppat.1000544

Helminth Genomics: The Implications for Human Health

Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman

PLoS Neglected Tropical Diseases:
Published 26 Oct 2009 | info:doi/10.1371/journal.pntd.0000538

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