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RosettaCon 2010

The Rosetta framework for macromolecular modeling, prediction and design is a widely used code (over 7,000 registered groups) with a large, dynamic developer community (over 200 members). The Rosetta community, which includes developers and users from industry and academia, meets once a year to discuss improvements to Rosetta, new applications of the Rosetta code to biological and chemical problems, and core code development. This special collection (PLoS One Special collection: RosettaCon 2010) presents recent developments from the Rosetta community, drawn from the groups participating in RosettaCon 2010.

The collection focuses on the publication of both the science and the reproducible computational workflow: each paper is accompanied by an annotated archive containing the code, scripts and data-sets needed to carry out the computational protocol described in the paper.

Articles are presented in order of publication date and new articles will be added to the Collection as they are published.

Editorial oversight, and coordination of the peer-review, was provided by Vladimir Uversky, PLoS ONE Academic Editor.

Image Credit: Chris Poultney, Richard Bonneau, New York University

Collection Citation: RosettaCon 2010 (2011) PLoS Collections: http://www.ploscollections.org/RosettaCon2010

 
 

Overview Top

The 2010 Rosetta Developers Meeting: Macromolecular Prediction and Design Meets Reproducible Publishing

P. Douglas Renfrew, Gabrielle Campbell, Charlie E. M. Strauss, Richard Bonneau

PLoS ONE:
Published 31 Aug 2011 | info:doi/10.1371/journal.pone.0022431
 

Research Articles Top

Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design

P. Douglas Renfrew, Eun Jung Choi, Richard Bonneau, Brian Kuhlman

PLoS ONE:
Published 14 Mar 2012 | info:doi/10.1371/journal.pone.0032637

Rational Design of Temperature-Sensitive Alleles Using Computational Structure Prediction

Christopher S. Poultney, Glenn L. Butterfoss, Michelle R. Gutwein, Kevin Drew, David Gresham, Kristin C. Gunsalus, Dennis E. Shasha, Richard Bonneau

PLoS ONE:
Published 02 Sep 2011 | info:doi/10.1371/journal.pone.0023947

RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

Po-Ssu Huang, Yih-En Andrew Ban, Florian Richter, Ingemar Andre, Robert Vernon, William R. Schief, David Baker

PLoS ONE:
Published 31 Aug 2011 | info:doi/10.1371/journal.pone.0024109

Generalized Fragment Picking in Rosetta: Design, Protocols and Applications

Dominik Gront, Daniel W. Kulp, Robert M. Vernon, Charlie E. M. Strauss, David Baker

PLoS ONE:
Published 24 Aug 2011 | info:doi/10.1371/journal.pone.0023294

Real-Time PyMOL Visualization for Rosetta and PyRosetta

Evan H. Baugh, Sergey Lyskov, Brian D. Weitzner, Jeffrey J. Gray

PLoS ONE:
Published 16 Aug 2011 | info:doi/10.1371/journal.pone.0021931

Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, Brian D. Weitzner, Pravin Muthu, Hannah Bergman, Jeffrey J. Gray

PLoS ONE:
Published 02 Aug 2011 | info:doi/10.1371/journal.pone.0022477

Modeling Disordered Regions in Proteins Using Rosetta

Ray Yu-Ruei Wang, Yan Han, Kristina Krassovsky, William Sheffler, Michael Tyka, David Baker

PLoS ONE:
Published 29 Jul 2011 | info:doi/10.1371/journal.pone.0022060

Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design

Colin A. Smith, Tanja Kortemme

PLoS ONE:
Published 18 Jul 2011 | info:doi/10.1371/journal.pone.0020451

A Generic Program for Multistate Protein Design

Andrew Leaver-Fay, Ron Jacak, P. Benjamin Stranges, Brian Kuhlman

PLoS ONE:
Published 06 Jul 2011 | info:doi/10.1371/journal.pone.0020937

RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite

Sarel J. Fleishman, Andrew Leaver-Fay, Jacob E. Corn, Eva-Maria Strauch, Sagar D. Khare, Nobuyasu Koga, Justin Ashworth, Paul Murphy, Florian Richter, Gordon Lemmon, Jens Meiler, David Baker

PLoS ONE:
Published 24 Jun 2011 | info:doi/10.1371/journal.pone.0020161

Modeling Symmetric Macromolecular Structures in Rosetta3

Frank DiMaio, Andrew Leaver-Fay, Phil Bradley, David Baker, Ingemar André

PLoS ONE:
Published 22 Jun 2011 | info:doi/10.1371/journal.pone.0020450

Anchored Design of Protein-Protein Interfaces

Steven M. Lewis, Brian A. Kuhlman

PLoS ONE:
Published 17 Jun 2011 | info:doi/10.1371/journal.pone.0020872

Four Small Puzzles That Rosetta Doesn't Solve

Rhiju Das

PLoS ONE:
Published 20 May 2011 | info:doi/10.1371/journal.pone.0020044

De Novo Enzyme Design Using Rosetta3

Florian Richter, Andrew Leaver-Fay, Sagar D. Khare, Sinisa Bjelic, David Baker

PLoS ONE:
Published 16 May 2011 | info:doi/10.1371/journal.pone.0019230

Rosetta FlexPepDock ab-initio: Simultaneous Folding, Docking and Refinement of Peptides onto Their Receptors

Barak Raveh, Nir London, Lior Zimmerman, Ora Schueler-Furman

PLoS ONE:
Published 29 Apr 2011 | info:doi/10.1371/journal.pone.0018934

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