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PLoS Genetics: Aging: Bench to Bedside

This collection focuses on a rapidly evolving field in which the study of both species-specific and ubiquitous aging mechanisms informs the biological process of aging. Yet the field is not without substantial controversy. Differing views arise as we come to understand aging across model systems — from bacteria to humans.

Collection Editors: Nicholas Katsanis (Duke University) and Susan M. Rosenberg (Baylor College of Medicine).

Download: Complete Collection (1 MB PDF).

Image Credit: The Keane family, PLoS Biology 4(4): e119.

 
 

Editorials Top

An Age-Old Problem

Nicholas Katsanis, Susan M Rosenberg

PLoS Genetics:
Published 23 Feb 2007 | info:doi/10.1371/journal.pgen.0030037

Entropy Explains Aging, Genetic Determinism Explains Longevity, and Undefined Terminology Explains Misunderstanding Both

Leonard Hayflick

PLoS Genetics:
Published 14 Dec 2007 | info:doi/10.1371/journal.pgen.0030220
 

Perspective Top

A Bacterial Kind of Aging

Thomas Nyström

PLoS Genetics:
Published 14 Dec 2007 | info:doi/10.1371/journal.pgen.0030224
 

Reviews Top

The Role of Mitochondrial DNA Mutations in Mammalian Aging

Gregory C Kujoth, Patrick C Bradshaw, Suraiya Haroon, Tomas A Prolla

PLoS Genetics:
Published 23 Feb 2007 | info:doi/10.1371/journal.pgen.0030024

Dietary Restriction in Drosophila: Delayed Aging or Experimental Artefact?

Matthew D. W Piper, Linda Partridge

PLoS Genetics:
Published 27 Apr 2007 | info:doi/10.1371/journal.pgen.0030057

Recent Developments in Yeast Aging

Matt Kaeberlein, Christopher R Burtner, Brian K Kennedy

PLoS Genetics:
Published 25 May 2007 | info:doi/10.1371/journal.pgen.0030084

Genetic Determinants of Human Health Span and Life Span: Progress and New Opportunities

George M Martin, Aviv Bergman, Nir Barzilai

PLoS Genetics:
Published 27 Jul 2007 | info:doi/10.1371/journal.pgen.0030125

Genetics of Aging in Caenorhabditis elegans

Adam Antebi

PLoS Genetics:
Published 28 Sep 2007 | info:doi/10.1371/journal.pgen.0030129

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