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Table of Contents: PLoS Pathogens' Pearls

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Image Credit: Illustration by Pat Margis (PLoS).
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PLoS Pathogens presents an Open Access compendium of the "lessons-that-last." This section, founded by Dr. Hiten Madhani and now edited by Drs Richard Condit, William Goldman, Joseph Heitman, Laura Knoll, Virginia Miller, Vincent Racaniello and Heather True, is a living collection of short educational and highly useful articles that address topics of relevance and importance within the wide-ranging field of pathogens research, with insights tailored to graduate students and post-docs.

Editorial

“Pearls”: A New Type of Open-Access Educational Resource

Hiten D. Madhani, Kasturi Haldar, Grant McFadden

Pearls

Plant Virus Ecology

Marilyn J. Roossinck

Immune Regulation during Helminth Infections

Natasha M. Girgis, Uma Mahesh Gundra, P'ng Loke

Parasites FeS Up: Iron-Sulfur Cluster Biogenesis in Eukaryotic Pathogens

Teegan A. Dellibovi-Ragheb, Jolyn E. Gisselberg, Sean T. Prigge

Fifty Shades of Immune Defense

Michael F. Criscitiello, Paul de Figueiredo

The Importance of Prions

Glenn C. Telling

Loss and Retention of RNA Interference in Fungi and Parasites

Francisco E. Nicolás, Santiago Torres-Martínez, Rosa M. Ruiz-Vázquez

Make It, Take It, or Leave It: Heme Metabolism of Parasites

Luděk Kořený, Miroslav Oborník, Julius Lukeš

Innate Sensing of Chitin and Chitosan

Chelsea L. Bueter, Charles A. Specht, Stuart M. Levitz

Pneumocystis: Where Does It Live?

Francis Gigliotti, Terry W. Wright

Aneuploidy and Drug Resistance in Pathogenic Fungi

Kyung J. Kwon-Chung, Yun C. Chang

Norovirus Immunity and the Great Escape

Kari Debbink, Lisa C. Lindesmith, Eric F. Donaldson, Ralph S. Baric

Copper at the Front Line of the Host-Pathogen Battle

Richard A. Festa, Dennis J. Thiele

Trichomonosis, a Common Curable STI, and Prostate Carcinogenesis—A Proposed Molecular Mechanism

Siobhan Sutcliffe, Calvin Neace, Nancy S. Magnuson, Raymond Reeves, J. F. Alderete

Host Defense and Tolerance: Unique Challenges in the Placenta

Varvara B. Zeldovich, Anna I. Bakardjiev

Phagocyte Responses to Protozoan Infection and How Toxoplasma gondii Meets the Challenge

Eric Y. Denkers, Anne G. Schneider, Sara B. Cohen, Barbara A. Butcher

Identifying Host Factors That Regulate Viral Infection

Tien-Huei Hsu, Katherine R. Spindler

Gastrointestinal Cell Mediated Immunity and the Microsporidia

Magali M. Moretto, Imtiaz A. Khan, Louis M. Weiss

Polydnaviruses as Symbionts and Gene Delivery Systems

Michael R. Strand, Gaelen R. Burke

Hydrophobins—Unique Fungal Proteins

Jagadeesh Bayry, Vishukumar Aimanianda, J. Iñaki Guijarro, Margaret Sunde, Jean-Paul Latgé

Influence of Microbiota on Viral Infections

Jessica Wilks, Tatyana Golovkina

Type III Secretion in Yersinia: Injectisome or Not?

Tomas Edgren, Åke Forsberg, Roland Rosqvist, Hans Wolf-Watz

Five Questions on Prion Diseases

Adriano Aguzzi, Caihong Zhu

Fungal Biofilms

Saranna Fanning, Aaron P. Mitchell

A Foot in the Door for Dermatophyte Research

Rebecca Rashid Achterman, Theodore C. White

New Insights into Blastocystis spp.: A Potential Link with Irritable Bowel Syndrome

Philippe Poirier, Ivan Wawrzyniak, Christian P. Vivarès, Frédéric Delbac, Hicham El Alaoui

Selecting an Invertebrate Model Host for the Study of Fungal Pathogenesis

Athanasios Desalermos, Beth Burgwyn Fuchs, Eleftherios Mylonakis

Sexual Development in Plasmodium: Lessons from Functional Analyses

David S. Guttery, Anthony A. Holder, Rita Tewari

Sequence Divergent RXLR Effectors Share a Structural Fold Conserved across Plant Pathogenic Oomycete Species

Joe Win, Ksenia V. Krasileva, Sophien Kamoun, Ken Shirasu, Brian J. Staskawicz, Mark J. Banfield

“Persisters”: Survival at the Cellular Level

Clinton C. Dawson, Chaidan Intapa, Mary Ann Jabra-Rizk

Innate Immune Sensing of DNA

Shruti Sharma, Katherine A. Fitzgerald

Viral Encephalomyelitis

Diane E. Griffin

Pathogenesis of the 1918 Pandemic Influenza Virus

Tokiko Watanabe, Yoshihiro Kawaoka

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

Brian M. Peters, Mark E. Shirtliff, Mary Ann Jabra-Rizk

RNA Virus Replication Complexes

Yizhi Jane Tao, Qiaozhen Ye

The Deadly Chytrid Fungus: A Story of an Emerging Pathogen

Erica Bree Rosenblum, Jamie Voyles, Thomas J. Poorten, Jason E. Stajich

The Inflammasomes

Mohamed Lamkanfi, Vishva M. Dixit

The Photobiology of Microbial Pathogenesis

Alexander Idnurm, Sean Crosson

Anatomy of Viral Persistence

Michael B. A. Oldstone