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PLoS Pathogens' Pearls

PLoS Pathogens presents an Open Access compendium of the "lessons-that-last." This section, founded by Dr. Hiten Madhani and now edited by Drs William Goldman, Joseph Heitman, Laura Knoll, Virginia Miller, Vincent Racaniello and Heather True, is a living collection of short educational and highly useful articles that address topics of relevance and importance within the wide-ranging field of pathogens research, with insights tailored to graduate students and post-docs.

Image Credit: Illustration by Pat Margis (PLoS).

Editorial Top

“Pearls”: A New Type of Open-Access Educational Resource

Hiten D. Madhani, Kasturi Haldar, Grant McFadden

PLoS Pathogens:
Published 26 Jun 2009 | info:doi/10.1371/journal.ppat.1000499

Pearls Top

Virus and Host Determinants of West Nile Virus Pathogenesis

Michael S. Diamond

PLoS Pathogens:
Published 26 Jun 2009 | info:doi/10.1371/journal.ppat.1000452

Anatomy of Viral Persistence

Michael B. A. Oldstone

PLoS Pathogens:
Published 31 Jul 2009 | info:doi/10.1371/journal.ppat.1000523

Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance

Leah E. Cowen

PLoS Pathogens:
Published 28 Aug 2009 | info:doi/10.1371/journal.ppat.1000471

Five Questions about Microsporidia

Patrick Keeling

PLoS Pathogens:
Published 25 Sep 2009 | info:doi/10.1371/journal.ppat.1000489

Advances in Parasite Genomics: From Sequences to Regulatory Networks

Elizabeth A. Winzeler

PLoS Pathogens:
Published 30 Oct 2009 | info:doi/10.1371/journal.ppat.1000649

The Photobiology of Microbial Pathogenesis

Alexander Idnurm, Sean Crosson

PLoS Pathogens:
Published 26 Nov 2009 | info:doi/10.1371/journal.ppat.1000470

The Inflammasomes

Mohamed Lamkanfi, Vishva M. Dixit

PLoS Pathogens:
Published 24 Dec 2009 | info:doi/10.1371/journal.ppat.1000510

The Deadly Chytrid Fungus: A Story of an Emerging Pathogen

Erica Bree Rosenblum, Jamie Voyles, Thomas J. Poorten, Jason E. Stajich

PLoS Pathogens:
Published 29 Jan 2010 | info:doi/10.1371/journal.ppat.1000550

Five Questions about Viruses and MicroRNAs

Bryan R. Cullen

PLoS Pathogens:
Published 26 Feb 2010 | info:doi/10.1371/journal.ppat.1000787

Expansion, Maintenance, and Memory in NK and T Cells during Viral Infections: Responding to Pressures for Defense and Regulation

Christine A. Biron

PLoS Pathogens:
Published 26 Mar 2010 | info:doi/10.1371/journal.ppat.1000816

Innate Recognition of Fungal Cell Walls

Stuart M. Levitz

PLoS Pathogens:
Published 22 Apr 2010 | info:doi/10.1371/journal.ppat.1000758

Candida albicans Interactions with Bacteria in the Context of Human Health and Disease

Diana K. Morales, Deborah A. Hogan

PLoS Pathogens:
Published 29 Apr 2010 | info:doi/10.1371/journal.ppat.1000886

The Microbiota and Allergies/Asthma

Gary B. Huffnagle

PLoS Pathogens:
Published 27 May 2010 | info:doi/10.1371/journal.ppat.1000549

Entry and Fusion of Emerging Paramyxoviruses

Rebecca Ellis Dutch

PLoS Pathogens:
Published 24 Jun 2010 | info:doi/10.1371/journal.ppat.1000881

Paramyxovirus Entry and Targeted Vectors for Cancer Therapy

Roberto Cattaneo

PLoS Pathogens:
Published 24 Jun 2010 | info:doi/10.1371/journal.ppat.1000973

RNA Virus Replication Complexes

Yizhi Jane Tao, Qiaozhen Ye

PLoS Pathogens:
Published 22 Jul 2010 | info:doi/10.1371/journal.ppat.1000943

The Role of Chemokines during Viral Infection of the CNS

Martin P. Hosking, Thomas E. Lane

PLoS Pathogens:
Published 29 Jul 2010 | info:doi/10.1371/journal.ppat.1000937

The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

Eric P. Skaar

PLoS Pathogens:
Published 12 Aug 2010 | info:doi/10.1371/journal.ppat.1000949

Norovirus Gastroenteritis, Carbohydrate Receptors, and Animal Models

Ming Tan, Xi Jiang

PLoS Pathogens:
Published 26 Aug 2010 | info:doi/10.1371/journal.ppat.1000983

Are Members of the Fungal Genus Pneumocystis (a) Commensals; (b) Opportunists; (c) Pathogens; or (d) All of the Above?

Melanie T. Cushion

PLoS Pathogens:
Published 23 Sep 2010 | info:doi/10.1371/journal.ppat.1001009

Retroviral RNA Dimerization and Packaging: The What, How, When, Where, and Why

Silas F. Johnson, Alice Telesnitsky

PLoS Pathogens:
Published 07 Oct 2010 | info:doi/10.1371/journal.ppat.1001007

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

Brian M. Peters, Mark E. Shirtliff, Mary Ann Jabra-Rizk

PLoS Pathogens:
Published 28 Oct 2010 | info:doi/10.1371/journal.ppat.1001067

Herpes Simplex Virus Reorganizes the Cellular DNA Repair and Protein Quality Control Machinery

Sandra K. Weller

PLoS Pathogens:
Published 24 Nov 2010 | info:doi/10.1371/journal.ppat.1001105

Coming of Age—Sexual Reproduction in Candida Species

Richard J. Bennett

PLoS Pathogens:
Published 23 Dec 2010 | info:doi/10.1371/journal.ppat.1001155

Pathogenesis of the 1918 Pandemic Influenza Virus

Tokiko Watanabe, Yoshihiro Kawaoka

PLoS Pathogens:
Published 27 Jan 2011 | info:doi/10.1371/journal.ppat.1001218

New Models of Microsporidiosis: Infections in Zebrafish, C. elegans, and Honey Bee

Emily R. Troemel

PLoS Pathogens:
Published 17 Feb 2011 | info:doi/10.1371/journal.ppat.1001243

Viral Encephalomyelitis

Diane E. Griffin

PLoS Pathogens:
Published 24 Mar 2011 | info:doi/10.1371/journal.ppat.1002004

Innate Immune Sensing of DNA

Shruti Sharma, Katherine A. Fitzgerald

PLoS Pathogens:
Published 21 Apr 2011 | info:doi/10.1371/journal.ppat.1001310

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

Judith E. Allen, Thomas A. Wynn

PLoS Pathogens:
Published 12 May 2011 | info:doi/10.1371/journal.ppat.1002003

Impact of Endofungal Bacteria on Infection Biology, Food Safety, and Drug Development

Gerald Lackner, Christian Hertweck

PLoS Pathogens:
Published 30 Jun 2011 | info:doi/10.1371/journal.ppat.1002096

“Persisters”: Survival at the Cellular Level

Clinton C. Dawson, Chaidan Intapa, Mary Ann Jabra-Rizk

PLoS Pathogens:
Published 28 Jul 2011 | info:doi/10.1371/journal.ppat.1002121

Exploiting and Subverting Tor Signaling in the Pathogenesis of Fungi, Parasites, and Viruses

Cecelia A. Shertz, Maria E. Cardenas

PLoS Pathogens:
Published 29 Sep 2011 | info:doi/10.1371/journal.ppat.1002269

Quorum Sensing in Fungi: Q&A

Hiten D. Madhani

PLoS Pathogens:
Published 27 Oct 2011 | info:doi/10.1371/journal.ppat.1002301

Microbial Spy Games and Host Response: Roles of a Pseudomonas aeruginosa Small Molecule in Communication with Other Species

Lucja M. Jarosz, Ekaterina S. Ovchinnikova, Michael M. Meijler, Bastiaan P. Krom

PLoS Pathogens:
Published 17 Nov 2011 | info:doi/10.1371/journal.ppat.1002312

Comparative Pathobiology of Fungal Pathogens of Plants and Animals

Martin B. Dickman, Paul de Figueiredo

PLoS Pathogens:
Published 15 Dec 2011 | info:doi/10.1371/journal.ppat.1002324

Five Questions about Non-Mevalonate Isoprenoid Biosynthesis

Audrey R. Odom

PLoS Pathogens:
Published 22 Dec 2011 | info:doi/10.1371/journal.ppat.1002323

Zebrafish: A See-Through Host and a Fluorescent Toolbox to Probe Host–Pathogen Interaction

David M. Tobin, Robin C. May, Robert T. Wheeler

PLoS Pathogens:
Published 05 Jan 2012 | info:doi/10.1371/journal.ppat.1002349

Sequence Divergent RXLR Effectors Share a Structural Fold Conserved across Plant Pathogenic Oomycete Species

Joe Win, Ksenia V. Krasileva, Sophien Kamoun, Ken Shirasu, Brian J. Staskawicz, Mark J. Banfield

PLoS Pathogens:
Published 12 Jan 2012 | info:doi/10.1371/journal.ppat.1002400

Sexual Development in Plasmodium: Lessons from Functional Analyses

David S. Guttery, Anthony A. Holder, Rita Tewari

PLoS Pathogens:
Published 19 Jan 2012 | info:doi/10.1371/journal.ppat.1002404

How Do Bacteria Know They Are on a Surface and Regulate Their Response to an Adhering State?

Henk J. Busscher, Henny C. van der Mei

PLoS Pathogens:
Published 26 Jan 2012 | info:doi/10.1371/journal.ppat.1002440

Selecting an Invertebrate Model Host for the Study of Fungal Pathogenesis

Athanasios Desalermos, Beth Burgwyn Fuchs, Eleftherios Mylonakis

PLoS Pathogens:
Published 02 Feb 2012 | info:doi/10.1371/journal.ppat.1002451

How Do Microbial Pathogens Make CENs?

Kaustuv Sanyal

PLoS Pathogens:
Published 09 Feb 2012 | info:doi/10.1371/journal.ppat.1002463