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Research Article

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor

  • Alex N. Bullock,

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Santina Russo,

    Affiliation: Swiss Light Source, Paul Scherrer Institut, Villigen PSI, Switzerland

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  • Ann Amos,

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Nicholas Pagano,

    Affiliation: Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Strasse, Marburg, Germany

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  • Howard Bregman,

    Affiliation: Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    Current address: Amgen Inc., Cambridge, Massachusetts, United States of America

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  • Judit É. Debreczeni,

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Wen Hwa Lee,

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Frank von Delft,

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Eric Meggers,

    Affiliation: Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Strasse, Marburg, Germany

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  • Stefan Knapp mail

    stefan.knapp@sgc.ox.ac.uk

    Affiliation: University of Oxford, Structural Genomics Consortium, Oxford, United Kingdom

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  • Published: October 20, 2009
  • DOI: 10.1371/journal.pone.0007112
  • Published in PLOS ONE

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