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Research Article

Evaluation of Gene, Protein and Neurotrophin Expression in the Brain of Mice Exposed to Space Environment for 91 Days

  • Daniela Santucci,

    Affiliation: Behavioural Neuroscience Section, Cellular Biology and Neuroscience Department, Istituto Superiore di Sanità, Rome, Italy

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  • Fuminori Kawano,

    Affiliation: Graduate School of Medicine, Osaka University, Osaka, Japan

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  • Takashi Ohira,

    Affiliation: Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

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  • Masahiro Terada,

    Affiliation: Japan Aerospace Exploration Agency, Ibaraki, Japan

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  • Naoya Nakai,

    Affiliation: Graduate School of Medicine, Osaka University, Osaka, Japan

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  • Nadia Francia,

    Affiliation: Behavioural Neuroscience Section, Cellular Biology and Neuroscience Department, Istituto Superiore di Sanità, Rome, Italy

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  • Enrico Alleva,

    Affiliation: Behavioural Neuroscience Section, Cellular Biology and Neuroscience Department, Istituto Superiore di Sanità, Rome, Italy

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  • Luigi Aloe,

    Affiliation: Institute of Neurobiology and Molecular Medicine, CNR, European Brain Research Institute, Rome, Italy

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  • Toshimasa Ochiai,

    Affiliation: Mitsubishi Heavy Industries, Hyogo, Japan

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  • Ranieri Cancedda,

    Affiliation: DOBIG, University of Genova, Genova, Italy

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  • Katsumasa Goto,

    Affiliation: Graduate School of Health Sciences, Toyohashi SOZO University, Aichi, Japan

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  • Yoshinobu Ohira mail

    ohira@space.hss.osaka-u.ac.jp

    Affiliations: Graduate School of Medicine, Osaka University, Osaka, Japan, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

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  • Published: July 09, 2012
  • DOI: 10.1371/journal.pone.0040112
  • Published in PLOS ONE

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