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Research Article

The IG-DMR and the MEG3-DMR at Human Chromosome 14q32.2: Hierarchical Interaction and Distinct Functional Properties as Imprinting Control Centers

  • Masayo Kagami,

    Affiliation: Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan

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  • Maureen J. O'Sullivan,

    Affiliation: Department of Pathology, School of Medicine, Our Lady's Children's Hospital, Trinity College, Dublin, Ireland

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  • Andrew J. Green,

    Affiliations: National Center for Medical Genetics, University College Dublin, Our Lady's Hospital, Dublin, Ireland, School of Medicine and Medical Science, University College, Dublin, Ireland

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  • Yoshiyuki Watabe,

    Affiliation: Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan

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  • Osamu Arisaka,

    Affiliation: Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan

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  • Nobuhide Masawa,

    Affiliation: Department of Pathology, Dokkyo University School of Medicine, Tochigi, Japan

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  • Kentarou Matsuoka,

    Affiliation: Department of Pathology, National Center for Child Health and Development, Tokyo, Japan

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  • Maki Fukami,

    Affiliation: Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan

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  • Keiko Matsubara,

    Affiliation: Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan

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  • Fumiko Kato,

    Affiliation: Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan

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  • Anne C. Ferguson-Smith,

    Affiliation: Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

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  • Tsutomu Ogata mail

    tomogata@nch.go.jp

    Affiliation: Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan

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  • Published: June 17, 2010
  • DOI: 10.1371/journal.pgen.1000992
  • Published in PLOS Genetics

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