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Research Article

Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease

  • Alison R. Erickson equal contributor,

    equal contributor Contributed equally to this work with: Alison R. Erickson, Brandi L. Cantarel, Regina Lamendella, Claire M. Fraser, Robert L. Hettich

    Affiliations: Chemical Science Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America, Graduate School of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, United States of America

    X
  • Brandi L. Cantarel equal contributor,

    equal contributor Contributed equally to this work with: Alison R. Erickson, Brandi L. Cantarel, Regina Lamendella, Claire M. Fraser, Robert L. Hettich

    Affiliation: Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Regina Lamendella equal contributor,

    equal contributor Contributed equally to this work with: Alison R. Erickson, Brandi L. Cantarel, Regina Lamendella, Claire M. Fraser, Robert L. Hettich

    Affiliation: Department of Ecology, Earth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

    Current address: Juniata College, Biology Department, Huntingdon, Pennsylvania, United States of America

    X
  • Youssef Darzi,

    Affiliations: Bioinformatics and Eco-Systems Biology lab, Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium, Research Group of Microbiology (MICR), Faculty of Sciences and Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium

    X
  • Emmanuel F. Mongodin,

    Affiliation: Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Chongle Pan,

    Affiliation: Chemical Science Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

    X
  • Manesh Shah,

    Affiliation: Chemical Science Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

    X
  • Jonas Halfvarson,

    Affiliation: Department of Internal Medicine, Division of Gastroenterology, Örebro University Hospital and School of Health and Medical Sciences, Örebro University, Örebro, Sweden

    X
  • Curt Tysk,

    Affiliation: Department of Internal Medicine, Division of Gastroenterology, Örebro University Hospital and School of Health and Medical Sciences, Örebro University, Örebro, Sweden

    X
  • Bernard Henrissat,

    Affiliation: Architecture et Fonction des Macromolécules Biologiques, UMR6098, Centre national de la recherche scientifique, Universités Aix-Marseille I & II, Marseille, France

    X
  • Jeroen Raes,

    Affiliations: Bioinformatics and Eco-Systems Biology lab, Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium, Research Group of Microbiology (MICR), Faculty of Sciences and Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium

    X
  • Nathan C. Verberkmoes,

    Affiliation: Chemical Science Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

    X
  • Claire M. Fraser equal contributor,

    equal contributor Contributed equally to this work with: Alison R. Erickson, Brandi L. Cantarel, Regina Lamendella, Claire M. Fraser, Robert L. Hettich

    Affiliation: Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    These authors are joint Senior Authors.

    X
  • Robert L. Hettich equal contributor,

    equal contributor Contributed equally to this work with: Alison R. Erickson, Brandi L. Cantarel, Regina Lamendella, Claire M. Fraser, Robert L. Hettich

    Affiliation: Chemical Science Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

    These authors are joint Senior Authors.

    X
  • Janet K. Jansson mail

    jrjansson@lbl.gov

    Affiliation: Department of Ecology, Earth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

    These authors are joint Senior Authors.

    X
  • Published: November 28, 2012
  • DOI: 10.1371/journal.pone.0049138
  • Published in PLOS ONE

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